Coupled third-order simplified spherical harmonics and diffusion equation–based fluorescence tomographic imaging of liver cancer
نویسندگان
چکیده
منابع مشابه
A parallel adaptive finite element simplified spherical harmonics approximation solver for frequency domain fluorescence molecular imaging.
Fluorescence molecular imaging/tomography may play an important future role in preclinical research and clinical diagnostics. Time- and frequency-domain fluorescence imaging can acquire more measurement information than the continuous wave (CW) counterpart, improving the image quality of fluorescence molecular tomography. Although diffusion approximation (DA) theory has been extensively applied...
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We derived analytical solutions of the simplified spherical harmonics equations, an approximation of the radiative transfer equation, for infinitely extended scattering media. The derived equations are simple (sum of exponential functions) and quickly evaluated. We compared the solutions with Monte Carlo simulations in the steady-state and time domains and found much better agreement compared t...
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Fluorescence lifetime imaging microscopy (FLIM) is a well-established technique (Bastiaens and Squire 1999; Berezovska et al. 2003; Selvin 2000; Vogel et al. 2006) that combines microscopic techniques with time-resolved detection to provide high-resolution lifetime images of thin tissue sections. This chapter concerns the in vivo time domain imaging of fluorescent contrast agents embedded in de...
متن کاملA parallel adaptive finite element simplified spherical harmonics approximation solver
Fluorescence molecular imaging/tomography may play an important future role in preclinical research and clinical diagnostics. Time-and frequency-domain fluorescence imaging can acquire more measurement information than the continuous wave (CW) counterpart, improving the image quality of fluorescence molecular tomography. Although diffusion approximation (DA) theory has been extensively applied ...
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The use of higher order approximations to the Radiative transport equation, through simplified spherical harmonics expansion (SPN) in optical tomography are presented. At higher orders, the image reconstruction becomes highly under-determined due to the large increase in the number of unknowns which cannot be adequately recovered. However, reconstruction of diffuse parameters, namely optical ab...
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ژورنال
عنوان ژورنال: Journal of Biomedical Optics
سال: 2015
ISSN: 1083-3668
DOI: 10.1117/1.jbo.20.9.090502