Could successful (mitochondrial) networking help prevent Huntington's disease?

Could successful (mitochondrial) networking help prevent Huntington's disease?

Polyglutamine expansions in huntingtin (Htt) are known to cause the profound neurodegenerative disorder, Huntington's disease (HD). Mitochondrial dysfunction has long been implicated in the pathophysiology of HD, but the underlying mechanism remains obscure. An article by Costa et al in this months edition describes a smooth mechanistic cascade from the well-accepted upstream event that mutant ...

Applying Bioinfomatics Strategies in Huntingtons Disease Research

Digestive and nutritional considerations in celiac disease: could supplementation help?

Due to the increased immune activation in the intestinal tract of people with celiac disease, the digestive and absorptive processes of those affected may be compromised. Individuals with celiac disease are more susceptible to pancreatic insufficiencies, dysbiosis, lactase insufficiencies, and folic acid, vitamin B12, iron, and vitamin D deficiencies, as well as accelerated bone loss due to an ...

Mitochondrial replacement to prevent the transmission of mitochondrial DNA disease

M itochondrial medicine has seen major advances over recent years. The development of new genetic technology has enabled the genetic diagnosis to be established in an increasing number of patients. This has led to a recognition that mitochondrial diseases are not rare, but one of the most common group of genetic diseases. Associated with these advances, there have been undoubted improvements in...

Islam with the internet could do much to prevent disease.