Cospeciation of coronavirus and paramyxovirus with their bat hosts in the same geographical areas

Abstract Background Bat-borne viruses are relatively host specific. We hypothesize that this specificity is due to coevolution of the with their hosts. To test hypothesis, we investigated coronavirus and paramyxovirus bat Published nucleotide sequences RNA-dependent RNA polymerase (RdRp) gene 60 strains identified from 37 species, large (L) 36 29 cytochrome B ( cytB ) 35 species were analyzed for signals. Each signal detected was tested verified by global-fit cophylogenic analysis using software ParaFit, PACo, eMPRess. Results Significant signals in coronaviruses paramyxoviruses hosts, closely related hosts found carry viruses. Conclusions Our results suggest coevolve