Cortisol awakening response in late pregnancy in women with previous or ongoing depression

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Cortisol awakening response in late pregnancy in women with previous or ongoing depression

Pregnancy is associated with increased basal cortisol levels, and decreased hypothalamic-pituitary-adrenal (HPA) axis reactivity. The cortisol awakening response (CAR) is a measure of HPA-axis reactivity which has been reported to be increased in patients with ongoing depressive disorder and in individuals with remitted depression. In this study, we investigated HPA-axis reactivity in pregnant ...

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The cortisol awakening response and major depression: examining the evidence

A vast body of literature has revealed that dysregulation of the hypothalamic-pituitary-adrenal (HPA) stress axis is associated with etiology of major depressive disorder (MDD). There are many ways that the dysregulation of the HPA axis can be assessed: by sampling diurnal basal secretion and/or in response to a stress task, pharmacological challenge, and awakening. Here, we focus on the associ...

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Cortisol awakening response and subsequent depression: prospective longitudinal study

BACKGROUND Some studies have found an association between elevated cortisol and subsequent depression, but findings are inconsistent. The cortisol awakening response may be a more stable measure of hypothalamic-pituitary-adrenal function and potentially of stress reactivity. AIMS To investigate whether salivary cortisol, particularly the cortisol awakening response, is associated with subsequ...

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Parental history of depression or anxiety and the cortisol awakening response.

BACKGROUND It is unclear whether altered hypothalamic-pituitary-adrenal (HPA) axis regulation, which frequently accompanies depression and anxiety disorders, represents a trait rather than a state factor. AIMS To examine whether HPA axis dysregulation represents a biological vulnerability for these disorders, we compared cortisol levels in unaffected people with and without a parental history...

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State associations with the cortisol awakening response in healthy females.

The current study examined intra-individual relationships between the cortisol awakening response (CAR) and state sleep-related and psychosocial variables in a pooled design study. 12 healthy female participants (age range: 22-41 years.) were examined on 12 study days each, occurring at three-day intervals. Quantitative diaries capturing state sleep-related and psychosocial variables were fille...

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ژورنال

عنوان ژورنال: Psychoneuroendocrinology

سال: 2013

ISSN: 0306-4530

DOI: 10.1016/j.psyneuen.2013.08.007