Corticosteroid withdrawal in asthma.

Ulcerative colitis following introduction of zafirlukast and corticosteroid withdrawal in severe atopic asthma.

1. Faul JL, Leonard CT, Burke CM, Tormey VJ, Poulter LW. Fluticasone propionate induced alterations to lung function and the immunopathology of asthma over time. Thorax 1998; 53: 753±761. 2. Barnes PJ, Pedersen S. Efficacy and safety of inhaled corticosteroids in asthma. Am Rev Respir Dis 1993; 148: Suppl. 4, S1±S26. 3. Faul JL, Tormey W, Tormey V, Burke CM. High dose inhaled corticosteroids an...

Topical corticosteroid withdrawal in a pediatric patient

ED: emergency department TCS: topical corticosteroids INTRODUCTION Topical corticosteroids (TCS) are used frequently for various inflammatory conditions in dermatology. It is well known that the prolonged daily and inappropriate use of TCS may cause adverse effects such as atrophy, telangiectasia, and striae, among others. TCSwithdrawal has been described in adults but has been infrequently rep...

Inhaled corticosteroid dosage in asthma.

Corticosteroid resistance in chronic asthma.

Fifty-eight patients with chronic asthma in whom airflow obstruction was relieved by bronchodilator aerosols but not by oral corticosteroids were compared with 58 other chronic asthmatics who responded equally well to both treatments. The two groups were matched for age and sex. The only significant clinical differences between the two groups were that in the "corticosteroid-resistant" patients...

Asthma: beyond corticosteroid treatment

Asthma is one of the most common chronic diseases in the world, affecting over 300 million people. It is an inflammatory disorder characterized by bronchoconstriction and airway hyperresponsiveness, followed by inflammatory manifestations in the respiratory system. The prevalence of asthma is rising and there is a clinical need to develop more effective treatments. While corticosteroids (glucoc...