Corticolimbic metabolic dysregulation in euthymic older adults with bipolar disorder
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چکیده
منابع مشابه
Lithium for Older Adults with Bipolar Disorder
The use of lithium carbonate for the treatment of bipolar disorder in older adults is decreasing at a significant rate. This change in prescription pattern is occurring at a time when all evidence-based treatment guidelines and systematic reviews still recommend lithium as a first-line treatment for bipolar disorder. Despite having the strongest evidence base for effectiveness, lithium does pos...
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Convergent evidence supports regional dysfunction within a corticolimbic neural system that subserves emotional processing and regulation in adolescents and adults with bipolar disorder (BD), with abnormalities prominent within the amygdala and its major anterior paralimbic cortical connection sites including ventral anterior cingulate, orbitofrontal, insular and temporopolar cortices. Recent s...
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Methods: Participants, aged ≥60 years, were experiencing suboptimal response—defined as irritability, agitation, and mood lability or diminished ability to take care of basic personal needs as a result of their illness—to their current bipolar disorder medication. All patients had open-label, flexible-dose, sublingual asenapine added to their current medication for 12 weeks. Responses were eval...
متن کاملAttentional bias in euthymic bipolar I disorder.
Little is known about the nature of the relation between information-processing biases and affective traits in bipolar disorder. The present study was designed to investigate whether attentional biases are evident in persons diagnosed with bipolar disorder when they are in a positive mood state, and whether biases are related to indices of emotion regulation and to prior history of mood episode...
متن کاملNeurocognitive impairment in euthymic patients with bipolar affective disorder.
BACKGROUND Persistent impairments in neurocognitive function have been described in patients with bipolar disorder whose disease is in remission. However, methodological issues such as the effect of residual mood symptoms and hypercortisolaemia may confound such studies. AIMS To assess neurocognitive functioning in prospectively verified euthymic patients with bipolar disorder. METHOD Sixty...
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ژورنال
عنوان ژورنال: Journal of Psychiatric Research
سال: 2009
ISSN: 0022-3956
DOI: 10.1016/j.jpsychires.2008.08.001