Correlation Between Placental Histomorphology and Umbilical Cord Coiling Index in Preeclampsia

BACKGROUND
 Preeclampsia is a common hypertensive disorder of pregnancy and one the leading causes maternal health complications death globally. Both preeclampsia abnormal umbilical coiling have been reported to alter structure placenta significantly. Cases either two states; hypercoiling or hypocoiling, occurring in same documented. The type associated with varies different populations. extent changes coupled unknown. current study aimed at determining which state significantly alters placentae mothers therefore, predisposes them more adverse perinatal outcomes.
 
 METHODs
 An unmatched case-control was carried out Kenyatta National Hospital labor ward maternity theatre. Seventy (70) from diagnosis (cases) without complicated (controls) were collected. length cord number coils measured calculate index. A gross placental examination followed by biopsy tissue processing for light microscopy. Slides photographed several histological features analyzed terminal villi. Data this input into SPSS (Version 21.0) where mean values, standard deviations, frequency tables obtained. Appropriate parametric non-parametric tests used needed. P-value <0.05 considered statistically significant.
 RESULTS
 In study, index (UCI) cases controls 0.40 ± 0.18 0.22 0.08 coils/cm respectively. had greater UCI than (P = < 0.001). All case hypocoiled subdivision infarctions meconium stained. weight 519 g 578 respectively difference found be significant (p 0.031). controls, volume 542 cm3 638 cm3, There between subdivisions 0.001 0.028 respectively). highest absolute villous stroma, fibrin deposition, syncytial knots lowest fetal capillary surface area.
 CONCLUSION
 Hypocoiling alteration it observed hypercoiling. Early detection hypocoiling using ultrasound pregnancies may help clinicians identification that warrant close antenatal intrapartum monitoring thus reducing