Correlation Between Neutrophil-Lymphocyte Ratio, Platelets-Lymphocyte Ratio, and High-Resolution CT in Patients with COVID-19

Background: COVID-19 is a highly infectious disease that necessitates simple and rapid methods for recognising severe patients. Aims: To correlate between chest lesions in CT, neutrophil-lymphocyte ratio (NLR), platelets-lymphocytes patients with COVID-19, to detect their cut-off values as an early warning of Egyptian Subjects Methods: A cross-sectional study included 100 adult attending Ahmed Maher Teaching Hospital, Cairo, Egypt. Clinical, laboratory, radiological assessments were done. They classified according CT grades into three groups: seven normal 45 non-severe cases, 48 cases. Results: Dyspnoea was the most common symptom among cases (79.2%) fever (71.1%), while cough (85.7%) CT. The age, NLR, C-reactive protein (CRP), D-dimer significantly highest, absolute lymphocytes lowest. Highly significant positive correlations found D-dimer, CRP; correlation age; negative Using receiver operating characteristic analysis, areas under curve CRP, ferritin, platelet-lymphocyte 0.760, 0.698, 0.640, 0.627, 0.614, 0.595, respectively. optimal value NLR 2.50 0.74 specificity, 0.61 sensitivity, 67.5 accuracy. Conclusion: reliable easy-to-use predictor severity. (>2.5) should prompt prescription it could reveal essential influence further management.