Correlation-Based Inference for Linkage Disequilibrium With Multiple Alleles
نویسندگان
چکیده
منابع مشابه
Correlation-based inference for linkage disequilibrium with multiple alleles.
The correlation between alleles at a pair of genetic loci is a measure of linkage disequilibrium. The square of the sample correlation multiplied by sample size provides the usual test statistic for the hypothesis of no disequilibrium for loci with two alleles and this relation has proved useful for study design and marker selection. Nevertheless, this relation holds only in a diallelic case, a...
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ژورنال
عنوان ژورنال: Genetics
سال: 2008
ISSN: 1943-2631
DOI: 10.1534/genetics.108.089409