Correlation Analysis of Galectin-3 Serum Level in Obesity with and without Obesity

There are more than 3.4 million deaths every year in the world due to overweight and obesity. Obesity is a chronic proinflammatory condition marked by increased lipid adipose tissues, leading ectopic fat accumulation with levels of cytokines. causes progressive increase galectin-3 expression, especially visceral subcutaneous tissue experimental animals. Galectin-3 upregulated obesity defined as molecule that can cause insulin resistance. This study aims analyze differences between obese non-obese subjects. was cross-sectional study, using total 80 The conducted throughout August 2022. samples were grouped into based on Body Mass Index (BMI). measurement used Enzyme-Linked Immunosorbent Assay (ELISA) method. Statistical tests Mann-Whitney test Spearmen rho; results significant if p-value <0.05. divided groups, each group had 40 people. 0.9±0.36 ng/mL significantly higher group’s 0.43±0.11 ng/mL, (p<0.001). strong positive correlation BMI, (r=0.866, p<0.001). serum BMI. greater value galectin-3.