Correlates of Quantitative Measurement of BK Polyomavirus (BKV) DNA with Clinical Course of BKV Infection in Renal Transplant Patients
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منابع مشابه
Correlates of quantitative measurement of BK polyomavirus (BKV) DNA with clinical course of BKV infection in renal transplant patients.
BK virus-allograft nephropathy (BKVAN) is an increasingly recognized complication after kidney transplantation. Quantitative tests have been advocated to monitor patients, but data demonstrating their efficacy are relatively limited. We developed a real-time PCR assay to quantitate BK virus loads in the setting of renal transplantation, and we correlated the BK virus load with clinical course a...
متن کاملبررسی مولکولی فعالیت مجدد ویروس BK در ادرار بیماران پیوند کلیه
Background & Amis: BK polyomavirus (BKV) is common infection of childhood that persists in kidney epithelium. BKV reactivation characterized by viruria occurs in 35% to 57% of renal allograft recipients. BK virus was detected in serum samples in 6% to 29% of these patients. BKV-associated nephropathy occurs in as many as 8% of renal allograft recipients and may lead to . This study was carri...
متن کاملHuman polyomavirus BKV and renal disease.
Urinary shedding of BKV is increased in immunocomIn 1971, two human polyomaviruses were discovered, BK virus (BKV ) from the urine of a renal transplant promising conditions. BKV infection has been linked to occasional cases of cystitis in immunocompetent recipient (whose initials were B.K.) and JC virus (JCV ) from the brain of a patient (whose initials were J.C.) children, to glomerulonephrit...
متن کاملBKV QPCR detection and infection monitoring in renal transplant recipients.
BKV associated nephropathy (BKVAN) is a cause of renal dysfunction and loss of the graft in transplants. Viral primary infection is usually inapparent and then BKV establishes latency in kidneys. Reactivation occurs in immunocompromised conditions in renal transplant recipients who can develop a subclinical nephritis and eventually a BKV-associated interstitial nephritis or a BKVAN. In this stu...
متن کاملEarly BK polyomavirus (BKV) reactivation in donor kidney is a risk factor for development of BKV-associated nephropathy.
The pathogenesis of BK polyomavirus (BKV) infection and associated nephropathy in renal transplant recipients is not clearly understood. To gain insight, urine and plasma samples were collected from 112 renal transplant recipients before and after transplantation and tested for the presence of BKV by polymerase chain reaction. Detection of BKV infection very early (ie, 5 days) after transplanta...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2004
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.42.3.1176-1180.2004