Correction: Transcription factor clusters regulate genes in eukaryotic cells

Transcription factor clusters regulate genes in eukaryotic cells

Transcription is regulated through binding factors to gene promoters to activate or repress expression, however, the mechanisms by which factors find targets remain unclear. Using single-molecule fluorescence microscopy, we determined in vivo stoichiometry and spatiotemporal dynamics of a GFP tagged repressor, Mig1, from a paradigm signaling pathway of Saccharomyces cerevisiae. We find the repr...

Clustered transcription factor genes regulate nicotine biosynthesis in tobacco.

Tobacco (Nicotiana tabacum) synthesizes nicotine and related pyridine alkaloids in the root, and their synthesis increases upon herbivory on the leaf via a jasmonate-mediated signaling cascade. Regulatory NIC loci that positively regulate nicotine biosynthesis have been genetically identified, and their mutant alleles have been used to breed low-nicotine tobacco varieties. Here, we report that ...

Transcription Activation in Eukaryotic Cells

Transcription activation is the first step in eukaryotic gene expression. Gene regulation, which is about turning on and off expression of specific protein-coding genes in response to environmental changes, during development and in differentiated cells, widely occurs at the level of transcription activation. This is mostly achieved by DNA-binding proteins that can control the specificity of th...

Metal-responsive transcription factors that regulate iron, zinc, and copper homeostasis in eukaryotic cells.

ULTRAPETALA trxG genes interact with KANADI transcription factor genes to regulate Arabidopsis gynoecium patterning.

Organ formation relies upon precise patterns of gene expression that are under tight spatial and temporal regulation. Transcription patterns are specified by several cellular processes during development, including chromatin remodeling, but little is known about how chromatin-remodeling factors contribute to plant organogenesis. We demonstrate that the trithorax group (trxG) gene ULTRAPETALA1 (...