Corpora Amylacea in Neurodegenerative Diseases: Cause or Effect?

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Corpora Amylacea in Neurodegenerative Diseases: Cause or Effect?

The presence of corpora amylacea (CA) in the CNS is associated with both normal aging and neurodegenerative conditions including Alzheimer's disease (AD) and vascular dementia (VaD). CA are spherical bodies ranging in diameter (10-50 μm) and whose origin has been documented to be derived from both neural and glial sources. CA are reported to be primarily composed of glucose polymers, but approx...

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Corpora Amylacea of Brain Tissue from Neurodegenerative Diseases Are Stained with Specific Antifungal Antibodies

The origin and potential function of corpora amylacea (CA) remains largely unknown. Low numbers of CA are detected in the aging brain of normal individuals but they are abundant in the central nervous system of patients with neurodegenerative diseases. In the present study, we show that CA from patients diagnosed with Alzheimer's disease (AD) contain fungal proteins as detected by immunohistoch...

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Amyloid in prostatic corpora amylacea.

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ژورنال

عنوان ژورنال: International Journal of Neurology and Neurotherapy

سال: 2015

ISSN: 2378-3001

DOI: 10.23937/2378-3001/2/2/1031