Coronavirus virulence genes with main focus on SARS-CoV envelope gene
نویسندگان
چکیده
منابع مشابه
Evolutional insights on uncharacterized SARS coronavirus genes.
The complete genome of the severe acute respiratory syndrome coronavirus (SARS-CoV) and many of its variants has been determined by several laboratories. The genome contains fourteen predicted open reading frames (ORFs). However, a function had been clearly assigned for only six of these ORFs, in the viral replication, transcription and structural constituents. The others are herein referred to...
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Background & Objective: Coronavirus disease 2019 (COVID-19) is the most recent emerging viral disease. Defining the epidemiological aspects and factors influencing the susceptibility of the patients to COVID-19 has been an ongoing struggle. In the present study, we have investigated the connection between ABO histo-blood group phenotypes and the COVID-19. Methods:...
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Pharmacophore-based virtual screening is an effective, inexpensive and fast approach to discovering useful starting points for drug discovery. In this study, we developed a pharmacophore model for the main proteinase of severe acute respiratory syndrome coronavirus (SARS-CoV). Then we used this pharmacophore model to search NCI 3D database including 250, 251 compounds and identified 30 existing...
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ژورنال
عنوان ژورنال: Virus Research
سال: 2014
ISSN: 0168-1702
DOI: 10.1016/j.virusres.2014.07.024