Coronavirus non-structural protein 16: Evasion, attenuation, and possible treatments
نویسندگان
چکیده
منابع مشابه
Variable oligomerization modes in coronavirus non-structural protein 9.
Non-structural protein 9 (Nsp9) of coronaviruses is believed to bind single-stranded RNA in the viral replication complex. The crystal structure of Nsp9 of human coronavirus (HCoV) 229E reveals a novel disulfide-linked homodimer, which is very different from the previously reported Nsp9 dimer of SARS coronavirus. In contrast, the structure of the Cys69Ala mutant of HCoV-229E Nsp9 shows the same...
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ژورنال
عنوان ژورنال: Virus Research
سال: 2014
ISSN: 0168-1702
DOI: 10.1016/j.virusres.2014.09.009