Copper-induced oxidative stress inSaccharomyces cerevisiaetargets enzymes of the glycolytic pathway

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Copper-induced oxidative stress in Saccharomyces cerevisiae targets enzymes of the glycolytic pathway.

Increased cellular levels of reactive oxygen species are known to arise during exposure of organisms to elevated metal concentrations, but the consequences for cells in the context of metal toxicity are poorly characterized. Using two-dimensional gel electrophoresis, combined with immunodetection of protein carbonyls, we report here that exposure of the yeast Saccharomyces cerevisiae to copper ...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 2003

ISSN: 0014-5793

DOI: 10.1016/s0014-5793(03)01428-5