Conversion of choline methyl groups through trimethylamine into methane in the rumen
نویسندگان
چکیده
منابع مشابه
Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme.
Choline and trimethylamine (TMA) are small molecules that play central roles in biological processes throughout all kingdoms of life. These ubiquitous metabolites are linked through a single biochemical transformation, the conversion of choline to TMA by anaerobic microorganisms. This metabolic activity, which contributes to methanogenesis and human disease, has been known for over a century bu...
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[Methyl-14C]-choline incorporation into nude mice bearing tumor xenografts-correlation with [methyl-3H]-thymidine: A pilot study
Background: Many in vitro studies suggested that choline incorporation into many types of tumors is related to cell proliferation. Whether in vivo choline incorporation is related also to cell proliferation or not was my question. Therefore, the aim of this pilot study was to investigate the relationship of in vivo [methyl- 14C]-choline incorporation and in vivo [methyl-3H]- thymidine incorpora...
متن کاملStudies on the precursors of the methyl groups of choline in rat liver.
Since the original demonstrations by du Vigneaud et al. (l-4) that the methyl group of labeled methionine can be transferred intact to choline, considerable evidence has accumulated suggesting that this is not the only source of choline methyl groups. It was shown unequivocally that choline methyl groups can be synthesized de novo in germ-free rats receiving a diet devoid of methyl donors (5). ...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1978
ISSN: 0264-6021
DOI: 10.1042/bj1700529