CONVERSION OF C14-LABELED PROPIONATE, LACTATE, AND PYRUVATE TO ACETYL GROUPS IN THE RAT
نویسندگان
چکیده
منابع مشابه
The utilization in vitro of C14-labeled acetate and pyruvate by diaphragm muscle of rat.
The usefulness of the rat diaphragm technique of Gemmill in the study of carbohydrate metabolism of muscle in vitro has been demonstrated by the experiments of Gemmill (1, Z), Stadie (3, 4), Krahl and Cori (5), Krahl and Park (6), and Verzar and Wenner (7, 8). The adaptation of this technique to experiments by use of Cr4-labeled glucose was described in a previous paper (9). In those experiment...
متن کاملConversion of DL-lactate-2-C14 or -3-C14 or pyruvate-2-C14 to blood glucose in humans: effects of diabetes, insulin, tolbutamide, and glucose load.
متن کامل
Metabolism of C14 labeled glucose and pyruvate by rat diaphragm muscle in vitro.
The results of a number of earlier investigations (l-5) have shown that glucose utilization and glycogen synthesis in the isolated rat diaphragm are increased by the addition of insulin to the incubation medium. Insulin also increases the amount of glucose carbon metabolized by mammalian muscle to CO*, both in vitro (5) and in vivo (6). The rates of these three reactions are increased by the re...
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The metabolism of pyruvate and acetate has been widely investigated in a variety of organisms. Studies of pyruvate fermentation in yeast, as well as the aerobic metabolism of both compounds in animals and microorganisms, have established the import.ance of decarboxylation as an initial step in the anaerobic metabolism of pyruvate and of the central position of the Krebs tricarboxylic acid cycle...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1952
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)50868-7