Controlled trial of terfenadine and chlorpheniramine maleate in perennial rhinitis

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Controlled trial of terfenadine and chlorpheniramine maleate in perennial rhinitis.

A double-blind clinical trial in 60 patients with perennial rhinitis was conducted to compare the efficacy and side effects of two antihistamines, terfenadine and chlorpheniramine maleate, and placebo. There was no statistically significant difference in response between active treatments and placebo. Although side effects were more frequent with chlorpheniramine this also was not statistically...

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A Comparative Study of Fexofenadine with Chlorpheniramine Maleate and Betamethasone in Allergic Rhinitis

Objectives: This study was undertaken to compare the efficacy and safety of fexofenadine with chlorpheniramine and betamethasone in allergic rhinitis. Methods: This was a prospective observational study on 75 patients of allergic rhinitis. They were randomly divided into 3 groups of 25 patients each for receiving fexofenadine, chlorpheniramine and betamethasone respectively. Improvement of symp...

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Formulation and Evaluation of Medicated Chewing Gums of Chlorpheniramine Maleate

The aim of the present work is development and evaluation of Chlorpheniramine maleate medicated chewing gums and to study the influence of different plasticizers on physicochemical parameters and in vitro drug release profile. Chlorpheniramine maleate is used to relieve symptoms of allergy, hay fever and common cold. Prepared formulations are evaluated for thickness, hardness, weight variation,...

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Effect of Inhalation of Aromatherapy Oil on Patients with Perennial Allergic Rhinitis: A Randomized Controlled Trial

This study aimed to investigate the effects of aromatherapy oil inhalation on symptoms, quality of life, sleep quality, and fatigue level among adults with perennial allergic rhinitis (PAR). Fifty-four men and women aged between 20 and 60 were randomized to inhale aromatherapy oil containing essential oil from sandalwood, geranium, and Ravensara or almond oil (the placebo) for 5 minutes twice d...

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Randomised controlled trial of homoeopathy versus placebo in perennial allergic rhinitis with overview of four trial series.

OBJECTIVE To test the hypothesis that homoeopathy is a placebo by examining its effect in patients with allergic rhinitis and so contest the evidence from three previous trials in this series. DESIGN Randomised, double blind, placebo controlled, parallel group, multicentre study. SETTING Four general practices and a hospital ear, nose, and throat outpatient department. PARTICIPANTS 51 pat...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1982

ISSN: 0032-5473

DOI: 10.1136/pgmj.58.681.422