Controlled trial of Duogastrone in duodenal ulcer.

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Controlled trial of Duogastrone in duodenal ulcer.

A double-blind placebo-controlled trial of carbenoxolone, as 50 mg Duogastrone capsules, and in a dose of 200 mg daily for 12 weeks, was carried out in 40 ambulant subjects with endoscopically diganosed duodenal ulceration, of whom 34 were available for final analysis. Each patient was seen every two weeks and endoscoped at four, eight and 12 weeks. Serum carbenoxolone was measured at each visi...

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Double-blind controlled trial of amylopectin sulphate (Depepsen) in the symptomatic treatment of duodenal ulcer.

In a double-blind controlled trial amylopectin sulphate (Depepsen) had no significant advantage over placebo in the symptomatic treatment of duodenal ulcer.

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A controlled trial of carbenoxolone sodium capsules in the treatment of duodenal ulcer.

Carbenoxolone sodium is an effective agent promoting the healing of chronic gastric ulcers (Doll, Hill, Hutton, and Underwood, 1962; Doll, Hill, and Hutton, 1965; Horwich and Galloway, 1965; Turpie and Thomson, 1965). The drug is readily absorbed from the stomach and is largely excreted in bile (Iveson, Parke, and Williams, 1966). It is believed to have a local effect on the gastric mucosa thro...

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Controlled trial of maintenance cimetidine treatment in healed duodenal ulcer: short and long-term effects.

Forty-two patients with endoscopically diagnosed duodenal ulcer were studied in a double-blind trial after their ulcers had been healed with cimetidine. Cimetidine was effective in preventing relapse, only five of the 20 patients allocated to cimetidine 400 mg twice daily relapsing during the six months' treatment, compared with 16 of the 22 on placebo treatment (P less than 0.01). Cimetidine w...

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Randomised controlled trial of short term treatment to eradicate Helicobacter pylori in patients with duodenal ulcer.

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ژورنال

عنوان ژورنال: Gut

سال: 1977

ISSN: 0017-5749

DOI: 10.1136/gut.18.1.78