منابع مشابه
Arterial stents: modelling drug release and restenosis
Artery walls have three layers. The inner layer is the intima; this contains the endothelium, a layer of cells directly next to the blood which play an important role in controlling vascular tone, regulating transport into the wall and inhibiting smooth muscle cell proliferation and migration (Corti and Badimon, 2002). The middle layer is the media which is the muscular part of the wall, contai...
متن کاملRestenosis and drug-eluting stents.
The implantation of intracoronary stents for the treatment of coronary atherosclerotic disease is one of the most common percutaneous procedures. While the procedure brings long-term benefit for a large percentage of patients, a significant number of patients experience in-stent restenosis (ISR). ISR may be caused by a number of biological and procedural factors, including lesion characteristic...
متن کاملRestenosis of endovascular stents from stent compression.
OBJECTIVES We sought to determine the basis for restenosis within superficial femoral arteries (SFAs) and hemodialysis conduits treated with balloon-expandable stents. BACKGROUND Use of stents within coronary and peripheral vessels continues to increase exponentially. The mechanism of restenosis within stents placed at various vascular sites is not well understood. In particular, the implicat...
متن کاملDrug-eluting stents: the end of restenosis?
One of the major advancements in interventional cardiology has been the introduction of drug-eluting stents (DES). By incorporating anti-proliferative agents onto the surface of the stent, neointimal hyperplasia occurring within the stent, which is the main cause of in-stent restenosis (ISR), is markedly reduced. Stents coated with agents, like sirolimus or paclitaxel, when compared to bare met...
متن کامل‘Miracle stents’ - a future without restenosis
Over the last three decades, percutaneous coronary intervention (PCI) technology has revolutionized the field of cardiology. PCI began in the form of balloon angioplasty, and was followed by coronary stenting. In-Stent restenosis is the main limitation of coronary stenting, and has been delayed to some extent by the development of drug eluting stents. Coronary angioplasty with stenting is curre...
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ژورنال
عنوان ژورنال: Journal of Vascular Surgery
سال: 2000
ISSN: 0741-5214
DOI: 10.1016/s0741-5214(00)90137-x