Controlled release of anticanecr agents through hydrophilic ethylene-vinyl alcohol copolymer membranes.
نویسندگان
چکیده
منابع مشابه
Characteristics of ethylene vinyl alcohol copolymer (EVAL) mixtures.
PURPOSE To determine physical characteristics of mixtures of ethylene vinyl alcohol copolymer (EVAL) and metrizamide dissolved in dimethyl sulfoxide, liquid materials developed for embolization of arteriovenous malformations. METHODS EVAL and dimethyl sulfoxide were mixed in various proportions and sterilized. The viscosity and density of each mixture was measured. Precipitation times were de...
متن کاملstudy of ethylene/vinyl acetate transformation to ethylene/vinyl alcohol copolymer by nmr and dsc
hydrolysis of ethylene-vinyl acetate copolymer in alkaline conditions using two systems of naoh/methanol and koh/isopropanol has been studied and the formation of ethylene-vinyl alcohol copolymer was systematically examined using nmr spectroscopy and dsc measurements. vinyl acetate weight percentage and the degree of hydrolysis were calculated from nmr spectroscopy and it is shown that hydrolys...
متن کاملPotential Use of Ethylene Vinyl Acetate Copolymer Excipient in Oral Controlled Release Applications: a Literature Review
Ethylene vinyl acetate copolymer (EVA) has a successful commercial history in the pharmaceutical industry as a controlled release excipient. The usage covers a wide spectrum of parenteral applications ranging from transdermal drug delivery, contraceptive insertions, subcutaneous implants and mucosal contact forms. The importance and prominence of EVA in parenteral applications has inspired rese...
متن کاملEnhanced Controlled Transdermal Delivery of Mexazolam Using Ethylene-vinyl Acetate
Repeated oral administration of mexazolam, an anti-anxiety agent, may cause adverse effects such as gastric disturbance, drowsiness, and ataxia due to transiently high blood levels. Transdermal administration would avoid the systemic side effects and gastric disorders after oral administration. We have developed a matrix using ethylene-vinyl acetate (EVA), a heat-processible and flexible mat...
متن کاملEnhanced Controlled Transdermal Delivery of Mexazolam Using Ethylene-vinyl Acetate
Repeated oral administration of mexazolam, an anti-anxiety agent, may cause adverse effects such as gastric disturbance, drowsiness, and ataxia due to transiently high blood levels. Transdermal administration would avoid the systemic side effects and gastric disorders after oral administration. We have developed a matrix using ethylene-vinyl acetate (EVA), a heat-processible and flexible mat...
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ژورنال
عنوان ژورنال: membrane
سال: 1983
ISSN: 0385-1036,1884-6440
DOI: 10.5360/membrane.8.241