Control over DNA replication in time and space
نویسندگان
چکیده
منابع مشابه
DNA replication checkpoint control.
The eukaryotic cell cycle comprises two critical phases, DNA replication (S phase) and the subsequent distribution of an equivalent genome to each of two daughter cells at mitosis (M phase). A signal transduction cascade called the replication checkpoint has evolved to ensure that M phase does not occur prior to the completion of S phase. The mitotic regulators targeted by this checkpoint have ...
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All eukaryotic cells replicate segments of their genomes in a defined temporal sequence. In multicellular organisms, at least half of the genome is subject to changes in this temporal sequence during development. We now know that this temporal sequence and its developmentally regulated changes are conserved across distantly related species, suggesting that it either represents or reflects somet...
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In order to test hypotheses about changes in the environment induced by man, including climatic change, ecologists are sampling portions of the environment repeatedly across time. This paper describes a method for testing a space-time interaction in repeated ecological survey data, when there is no replication at the level of individual sampling units (sites). This methodological development is...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 2012
ISSN: 0014-5793
DOI: 10.1016/j.febslet.2012.07.042