Contractile reserve is not dependent solely upon changes in myocardial blood flow

Contractile reserve and coronary blood flow reserve in collateral-dependent myocardium.

Numerous studies in recent years have clearly demonstrated that viable myocardium with contractile dysfunction maintains a contractile reserve that can be unmasked by inotropic stimulation, such as by the infusion of low doses of dobutamine. Hence, low-dose dobutamine echocardiography (LDDE) has become firmly established as a diagnostic tool in patients with coronary artery disease (CAD) and le...

Myocardial Blood Flow and Flow Reserve

Background. Aging is associated with changes of the systolic blood pressure that may increase cardiac work and myocardial blood flow at rest and reduce the myocardial flow reserve. This might be misinterpreted as age-related impairment of the coronary vasodilator capacity. Methods and Results. Myocardial blood flow was quantified at rest and after administration of intravenous dipyridamole in 4...

Length-dependent changes in myocardial contractile state.

PARMLEY, WILLIAM W., AND LEONARD CHUCK. Length-dependent changes in myocardial contractile state. Am. J. Physiol. 224(5) : 11951199. 1973.-The present study describes an alteration of myocardial contractile state which is intimately associated with changes in muscle length. Seventy-one right ventricular cat papillary muscles were studied isometrically or isotonically in vitro. When muscle lengt...

Early changes in myocardial perfusion patterns after myocardial infarction: relation with contractile reserve and functional recovery.

OBJECTIVES The purpose of this study was to assess early temporal changes in myocardial perfusion pattern by myocardial contrast echocardiography (MCE) and their relation to myocardial viability in patients with reperfused acute myocardial infarction (AMI). BACKGROUND Myocardial contrast echocardiography no-reflow is associated with poor contractile recovery after AMI. However, little is know...

Only Female Age, and Not Blood Type, Is Associated with Ovarian Reserve