Continuous Light Does Not Affect Atherosclerosis in APOE*3-Leiden.CETP Mice
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چکیده
منابع مشابه
Ghrelin Receptor Deficiency does not Affect Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor-Null Mice
OBJECTIVE Ghrelin, a stomach-derived, secreted peptide, and its receptor (growth hormone secretagogue receptor, GHSR) are known to modulate food intake and energy homeostasis. The ghrelin system is also expressed broadly in cardiovascular tissues. Since ghrelin has been associated with anti-inflammatory and anti-atherogenic properties, but is also well known to promote obesity and impair glucos...
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Antigen presenting cells (APC) have the ability to present both extra-cellular and intra-cellular antigens via MHC class I molecules to CD8(+) T cells. The cross presentation of extra-cellular antigens is reduced in mice with deficient Antigen Peptide Transporter 1 (TAP1)-dependent MHC class I antigen presentation, and these mice are characterized by a diminished CD8(+) T cell population. We ha...
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Bacterial endotoxin (lipopolysaccharide; LPS) evokes in rodents an adaptive sickness behavior. It also produces changes in stress hormones secretion and activity of brain serotonergic and noradrenergic systems that have been implicated in stress responses, fear, and anxiety. Acoustic startle reflex (ASR) is regarded as a protective behavioral response that is enhanced in threatening situations ...
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BACKGROUND An elevated serum concentration of homocysteine (hyperhomocysteinemia) has been shown to disturb fracture healing. As the essential amino acid, methionine, is a precursor of homocysteine, we aimed to investigate whether excess methionine intake affects bone repair. MATERIAL/METHODS We analyzed bone repair in 2 groups of mice. One group was fed a methionine-rich diet (n=13), and the...
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Background: Alzheimer’s disease (AD) is characterized by brain accumulation of the amyloidpeptide (A ) that triggers a cascade of biochemical and cellular alterations resulting in the clinical phenotype of the disease. While numerous experiments addressed A toxicity, the mechanisms are still not fully understood. The receptor for advanced glycation end products (RAGE) binds A and was suggested ...
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ژورنال
عنوان ژورنال: Journal of Biological Rhythms
سال: 2020
ISSN: 0748-7304,1552-4531
DOI: 10.1177/0748730420951320