Continuous culture – making a comeback?

Is chloramphenicol making a comeback?

BACKGROUND Due to increasing antimicrobial resistance there has been renewed interest in old drugs that have fallen into disuse because of toxic side effects. OBJECTIVES To evaluate the susceptibility profile, in our hospital, of Enterobacteriaceae and Streptococcus pneumoniae isolates to chloramphenicol and to compare them with the susceptibility to amoxicillin-clavulanate. METHODS All iso...

Is chloroquine making a comeback?

Chloroquine began as a first-line antimalarial in 1946, the same year that the rock star Cher was born. Similar to Cher, chloroquine peaked in popularity in the early 1960s. Cher has famously made several major comebacks. Is it now chloroquine’s turn? For decades, chloroquine was a remarkably effective, safe, and inexpensive antimalarial. Optimism about effectiveness of chloroquine led public h...

A forgotten clinical sign making a comeback.

We report a case of Staphylococcus aureus infective endocarditis in a patient presenting with fever and rare cutaneous manifestations of Osler Nodes and Janeway Lesions. There had not been any distinct risk factors. His echocardiography subsequently revealed vegetation at the anterior mitral valve leaflet. As Staphylococcus aureus infective endocarditis is of utmost significance in morbidity an...

Hospital gardens are making a comeback.

Visitors to London’s Great Ormond Street Hospital may be in for a lovely surprise. Those who venture past the Peter Pan statue at the entrance, through the busy corridors, and into the middle of the hospital will eventually discover a little garden, secreted away from the hustle and bustle. Built on an abandoned boilerhouse roof, it is now a small retreat—quiet, peaceful, and sheltered. It is s...

Comeback victory.