Continued Expression of GATA3 Is Necessary for Cochlear Neurosensory Development
نویسندگان
چکیده
منابع مشابه
Continued Expression of GATA3 Is Necessary for Cochlear Neurosensory Development
Hair cells of the developing mammalian inner ear are progressively defined through cell fate restriction. This process culminates in the expression of the bHLH transcription factor Atoh1, which is necessary for differentiation of hair cells, but not for their specification. Loss of several genes will disrupt ear morphogenesis or arrest of neurosensory epithelia development. We previously showed...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0062046