Constraint-Induced Movement Therapy Overcomes the Intrinsic Axonal Growth–Inhibitory Signals in Stroke Rats

Constraint-induced movement therapy overcomes the intrinsic axonal growth-inhibitory signals in stroke rats.

BACKGROUND AND PURPOSE Constraint-induced movement therapy (CIMT) improves functional outcome in patients with stroke possibly through structural plasticity. We hypothesized that CIMT could enhance axonal growth by overcoming the intrinsic growth-inhibitory signals, leading eventually to improved behavioral performance in stroke rats. METHODS Focal cerebral ischemia was induced by intracerebr...

Constraint-induced movement therapy after stroke.

Constraint-induced movement therapy (CIMT) was developed to overcome upper limb impairments after stroke and is the most investigated intervention for the rehabilitation of patients. Original CIMT includes constraining of the non-paretic arm and task-oriented training. Modified versions also apply constraining of the non-paretic arm, but not as intensive as original CIMT. Behavioural strategies...

Constraint-induced movement therapy for upper extremities in stroke patients.

BACKGROUND In stroke patients, upper limb paresis affects many activities of daily life. Reducing disability is therefore a major aim of rehabilitation programmes for hemiparetic patients. Constraint-induced movement therapy (CIMT) is a current approach to stroke rehabilitation that implies the forced use and the massed practice of the affected arm by restraining the unaffected arm. OBJECTIVE...

Constraint-induced movement therapy.

Kunkel and colleagues 1 recently published an article on constraint-induced (CI) movement therapy for motor recovery in chronic stroke patients. They presented the results of an uncontrolled series of 5 stroke patients undergoing CI therapy. The authors also presented a review of five studies, including their own, concerning the effectiveness of CI therapy based on a calculation of effect sizes...

Constraint Induced Movement Therapy