Constitutive excessive erythrocytosis causes inflammation and increased vascular permeability in aged mouse brain
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چکیده
منابع مشابه
Constitutive excessive erythrocytosis causes inflammation and increased vascular permeability in aged mouse brain.
Excessive erythrocytosis results in severely increased blood viscosity that may compromise the vascular endothelium. Using our transgenic mouse model of excessive erythrocytosis we previously showed that despite altered brain endothelial cell morphology and an activated vasculature, brain vascular integrity was largely maintained up to 4-5 months of age. We now present data showing that persist...
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ژورنال
عنوان ژورنال: Brain Research
سال: 2013
ISSN: 0006-8993
DOI: 10.1016/j.brainres.2013.07.033