Consider Urogenital Schistosomiasis and Tuberculosis

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New research tools for urogenital schistosomiasis.

Approximately 200,000,000 people have schistosomiasis (schistosome infection). Among the schistosomes, Schistosoma haematobium is responsible for the most infections, which are present in 110 million people globally, mostly in sub-Saharan Africa. This pathogen causes an astonishing breadth of sequelae: hematuria, anemia, dysuria, stunting, uremia, bladder cancer, urosepsis, and human immunodefi...

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A Microfiltration Device for Urogenital Schistosomiasis Diagnostics

Schistosomiasis is a parasitic disease affecting over 200 million people worldwide. This study reports the design and development of a microfiltration device for isolating schistosome eggs in urine for rapid diagnostics of urogenital schistosomiasis. The design of the device comprises a linear array of microfluidic traps to immobilize and separate schistosome eggs. Sequential loading of individ...

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Examining the Relationship between Urogenital Schistosomiasis and HIV Infection

BACKGROUND Urogenital schistosomiasis, caused by infection with Schistosoma haematobium, is widespread and causes substantial morbidity on the African continent. The infection has been suggested as an unrecognized risk factor for incident HIV infection. Current guidelines recommend preventive chemotherapy, using praziquantel as a public health tool, to avert morbidity due to schistosomiasis. In...

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The microbiome in urogenital schistosomiasis and induced bladder pathologies

BACKGROUND Human schistosomiasis is a highly prevalent neglected tropical disease (NTD) caused by Schistosoma species. Research on the molecular mechanisms influencing the outcomes of bladder infection by Schistosoma haematobium is urgently needed to develop new diagnostics, therapeutics and infection prevention strategies. The objective of the research study was to determine the microbiome fea...

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Haematological Profile and Intensity of Urogenital Schistosomiasis in Ghanaian Children

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ژورنال

عنوان ژورنال: Deutsches Aerzteblatt Online

سال: 2019

ISSN: 1866-0452

DOI: 10.3238/arztebl.2019.0191b