منابع مشابه
The mevalonate auxotrophic mutant of Staphylococcus aureus can adapt to mevalonate depletion.
In this study, we attempted to adopt the auxotrophic mevalonate synthase mutant (ΔmvaS mutant) of Staphylococcus aureus to study whether a nongrowing but viable cell population is tolerant to bactericidal antibiotics. The mevalonate-depleted nongrowing ΔmvaS mutant was found tolerant to antibiotics. Surprisingly, after prolonged cultivation, we obtained stable ΔmvaS variants that were able to g...
متن کاملCellular consequences of inositol depletion.
The inositol-depletion hypothesis was suggested to explain the therapeutic mechanism of mood-stabilizing drugs. Focus was previously on the phosphatidylinositol signalling pathway and on the regulatory roles of Ins(3,4,5)P(3) and DAG (diacylglycerol). Recent findings indicate that inositol and inositol-containing molecules, including phosphoinositides and inositol phosphates, have signalling an...
متن کاملassessing the causes and consequences of occurrence of environment depletion cycle in kelardasht (diagnosis and theory)
in less developed or developing countries like iran, the developing plans, due to the governance of non-scientific approaches in the feasibility study phase, provoke destroying environment, nonsustainably development and ruining the land use planning of districts. countless experiences show that usually the solutions to solve the problems do not function properly as these unpleased consequences...
متن کاملPrevalence and consequences of nutritional depletion in lung transplant candidates.
Nutritional status was studied in lung transplant (LT) candidates. The hypotheses were that nutritional depletion was highly prevalent and lean body mass depletion was a risk factor for a higher mortality both before and after LT. Of 78 consecutive patients listed for LT, 16 (21%) died while on the waiting list, eight (10%) were alive awaiting LT, and 54 (69%) received a graft. Mean age was 42....
متن کاملOzone Depletion and Its Consequences for the Fluence of CarcinogenicSunlight1
A slight reduction of the ozone level over the northern hemisphere in the period 1969-1986 has been reported (D. Lindley, Nature (Lond.), 323: 293, 1988). Ozone measurements performed in Oslo are in agree ment with this. However, the ozone level for 1987 and 1988 was above normal, and no negative or positive trend is apparent for the last 10 years. The consequences of an ozone reduction for the...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2002
ISSN: 0021-9258
DOI: 10.1074/jbc.m111369200