Connexin 26 (GJB2) Gene-Related Deafness and Speech Intelligibility After Cochlear Implantation
نویسندگان
چکیده
منابع مشابه
Connexin-associated deafness and speech perception outcome of cochlear implantation.
OBJECTIVE To compare performance after cochlear implantation in children with mutations in connexin (Cx) 26 (GJB2) or Cx30 (GJB6) and children with deafness of unknown etiology. DESIGN Genetic analysis and speech perception evaluation was performed in the children with and without Cx mutations who had undergone cochlear implantation. Speech perception performance was retrospectively analyzed ...
متن کاملA genotype-phenotype correlation for GJB2 (connexin 26) deafness.
INTRODUCTION Mutations in GJB2 are the most common cause of non-syndromic autosomal recessive hearing impairment, ranging from mild to profound. Mutation analysis of this gene is widely available as a genetic diagnostic test. OBJECTIVE To assess a possible genotype-phenotype correlation for GJB2. DESIGN Retrospective analysis of audiometric data from people with hearing impairment, segregat...
متن کاملSpeech Perception Outcomes after Cochlear Implantation in Children with GJB2/DFNB1 associated Deafness.
BACKGROUND Cochlear implants (CI) for the rehabilitation of patients with profound or total bilateral sensorineural hypoacusis represent the initial use of electrical fields to provide audibility in cases where the use of sound amplifiers does not provide satisfactory results. AIMS To compare speech perception performance after cochlear implantation in children with connexin 26-associated dea...
متن کاملSpeech perception and speech intelligibility in children after cochlear implantation.
OBJECTIVE This study aimed to evaluate the long-term speech perception and speech intelligibility of congenitally and prelingually deaf children after cochlear implantation. It was a longitudinal study following 63 congenitally or prelingually deaf children up to 5 years after implantation. They each received a nucleus multichannel cochlear implant before they were 10 years old. METHODS Perce...
متن کاملSpeech development and auditory performance in children after cochlear implantation
Abstract Background: The aim of this study was to determine the auditory performance of congenitally deaf children and the effect of cochlear implantation (CI) on speech intelligibility. Methods: Aprospective study was undertaken on 47 children in a pediatric tertiary referral center for CI. All children were deaf prelingually and were younger than 8 years of age. They were followed up until 5...
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ژورنال
عنوان ژورنال: Otology & Neurotology
سال: 2004
ISSN: 1531-7129
DOI: 10.1097/00129492-200411000-00013