منابع مشابه
Peptide conjugation via CuAAC 'click' chemistry.
The copper (I)-catalyzed alkyne azide 1,3-dipolar cycloaddition (CuAAC) or 'click' reaction, is a highly versatile reaction that can be performed under a variety of reaction conditions including various solvents, a wide pH and temperature range, and using different copper sources, with or without additional ligands or reducing agents. This reaction is highly selective and can be performed in th...
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228 March 2014, Vol. 104, No. 3 (Suppl 1) Rationale for pneumococcal conjugate vaccine and rotavirus vaccine introduction into public immunisation programmes While progress has been made in preventing deaths due to some of the vaccine-preventable diseases (e.g. measles deaths reduced from 535 000 in 2000 to 139 000 by 2010), a greater proportion of vaccine-preventable deaths is now attributed t...
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Vaccination is one of the most valuable and cost-effective strategies available to medicine in the battle to prevent and control infectious diseases. It is considered to be one of the ten greatest public health achievements of the 20th century (1). In the Americas, vaccination has brought about the eradication of smallpox in 1970 and of polio in 1991; the interruption of indigenous measles tran...
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Production of glycoconjugate vaccines involves the chemical conjugation of glycans to an immunogenic carrier protein such as Cross-Reactive-Material-197 (CRM197). Instead of using glycans from natural sources recent vaccine development has been focusing on the use of synthetically defined minimal epitopes. While the glycan is structurally defined, the attachment sites on the protein are not. Fu...
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ژورنال
عنوان ژورنال: Research Outreach
سال: 2022
ISSN: ['2517-701X', '2517-7028']
DOI: https://doi.org/10.32907/ro-131-3076746848