Conjugated polymer-enhanced enantioselectivity in fluorescent sensing

Fluorescent/phosphorescent dual-emissive conjugated polymer dots for hypoxia bioimaging.

A kind of fluorescent/phosphorescent dual-emissive conjugated polyelectrolyte has been prepared by introducing phosphorescent platinum(ii) porphyrin (O2-sensitive) into a fluorene-based conjugated polyelectrolyte (O2-insensitive), which can form ultrasmall conjugated polymer dots (FP-Pdots) in the phosphate buffer solution (PBS) via self-assembly caused by their amphiphilic structures with hydr...

Self-assembled conjugated polymer spheres as fluorescent microresonators

Confinement of light inside an active medium cavity can amplify emission. Whispering gallery mode (WGM) is one of mechanisms that amplifies light effectively by confining it inside high-refractive-index microstructures, where light propagates along the circumference of a sphere via total internal reflection. Here we show that isolated single microspheres of 2-10 μm diameter, formed from self-as...

Fluorescent-conjugated polymer superquenching facilitates highly sensitive detection of proteases.

Sensor formats have been developed for detecting the activity of proteolytic enzymes based on fluorescent conjugated polymer superquenching. These sensors employ a reactive peptide sequence within a tether linking a quencher to a biotin. The peptide binds to sensors containing colocated biotin-binding protein and fluorescent polymer by means of biotin-biotin binding protein interactions, result...

Conjugated Polymer Nanoparticles in Bio- Sensing and Bio-Imaging

Conjugated Polymer Sensors: Design Principles towards Enhanced Versatility

A description of how semiconducting fluorescent polymers function as chemosensors for a variety of chemical vapors is presented. Amplification is achieved by transport of optically induced excitations throughout a polymer film. Careful and thoughtful design of polymer chemical structures is crucial to achieving high sensitivity towards nitroaromatic explosives such as trinitrotoluene (TNT) and ...