Congenital melanocytic nevus admixed with speckled lentiginous nevus

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Speckled lentiginous nevus: within the spectrum of congenital melanocytic nevi.

BACKGROUND Currently, there is disagreement as to whether speckled lentiginous nevi (nevi spili) are congenital or acquired pigmented lesions. Part of this controversy is related to the natural history of these lesions that often present at birth as hyperpigmented patches and then take several years to reach their more readily recognized spotted form. Arguments in favor of speckled lentiginous ...

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Giant congenital melanocytic nevus is usually defined as a melanocytic lesion present at birth that will reach a diameter ≥ 20 cm in adulthood. Its incidence is estimated in <1:20,000 newborns. Despite its rarity, this lesion is important because it may associate with severe complications such as malignant melanoma, affect the central nervous system (neurocutaneous melanosis), and have major ps...

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Congenital Melanocytic Nevus Syndrome: A Case Series.

Congenital melanocytic nevus syndrome (CMNS) is the result of an abnormal proliferation of melanocytes in the skin and central nervous system caused by progenitor-cell mutations during embryonic development. Mutations in the NRAS gene have been detected in many of these cells. We present 5 cases of giant congenital melanocytic nevus, 3 of them associated with CMNS; NRAS gene mutation was studie...

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Giant Congenital Melanocytic Nevus of the Buttock

Figure 1. Two-year-old boy with a giant congenital melanocytic nevus of the left buttock. Left, Center, Preoperative views. Right, Immediate view after excision and placement of the Integra bilayer matrix dressing. Figure 2. Left, Wound after removal of the silicone layer of the Integra bilayer matrix dressing. Right, Coverage of the wound with a split skin autograft.

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology

سال: 2013

ISSN: 0019-5154

DOI: 10.4103/0019-5154.108091