Congenital Giant Melanocytic Nevi
نویسندگان
چکیده
منابع مشابه
Congenital giant melanocytic nevi
Nevi are common skin tumors caused by abnormal overgrowth of cells from the epidermal and dermal layers of the skin. Most nevi are benign, but some pre-cancerous nevi must be monitored or removed. The giant congenital nevus is greater than 10 cm in size, pigmented and often hairy. Between 4% and 6% of these lesions will develop into a malignant melanoma. Since approximately 50% of the melanoma ...
متن کاملGiant congenital melanocytic nevi: a case report.
Congenital melanocytic naevi which are formed by the overgrowth of melanocytes, are present at birth, which are called as bathing trunk, coat-sleeve or stocking naevi, which are commonly found over the back and the thigh areas . The giant congenital naevi of sizes which are greater than 20 cm are pigmented and are often hairy. The risk of malignant melanoma for the giant naevi is approximately ...
متن کاملGiant Congenital Melanocytic Nevi and Neurocutaneous Melanosis
Introduction. The major medical concern with giant congenital melanocytic nevi CMN is high risk of developing cutaneous melanoma, leptomeningeal melanoma, and neurocutaneous melanocytosis. Case Report. A 30-year-old woman with a giant congenital melanocytic nevus covering nearly the entire right thoracodorsal region and multiple disseminated melanocytic nevi presented with neurological symptoms...
متن کاملCongenital Melanocytic Nevi
Figure 1. The surgical incision is marked for first-stage serial excision. DESCRIPTION A 4-year-old girl presented with congenital melanocytic nevus on the right forearm.
متن کاملGiant Congenital Melanocytic Nevi: An Update and Emerging Therapies
Giant congenital melanocytic nevi (GCMN) are a rare occurrence. Gain-of-function mutation in the NRAS gene is found to be associated with GCMN, causing abnormal proliferation of embryonic melanoblasts. The two major complications associated with GCMN are malignant melanoma and neurocutaneous melanosis. Treatment of GCMN has conventionally been surgical. However, the role of NRAS inhibitors and ...
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ژورنال
عنوان ژورنال: Rare Tumors
سال: 2009
ISSN: 2036-3613,2036-3613
DOI: 10.4081/rt.2009.e9