Confocal Fluorescence Microscopy and Confocal Raman Microspectroscopy of X-ray Irradiated LiF Crystals

Synchrotron Radiation Based Confocal X-ray Fluorescence and Absorption Microspectroscopy in Earth and Environmental Science

The latest developments in energy-dispersive X-ray detection technology combined with the use of sophisticated X-ray detector optics open new avenues for the determination of 2D/ 3D distribution of (trace) elements within the investigated samples on the microscopic scale. This work illustrates the development and applications of synchrotron radiation based micro-XRF/XAS imaging towards a fully ...

Imaging of Scleral Collagen Deformation Using Combined Confocal Raman Microspectroscopy and Polarized Light Microscopy Techniques

This work presents an optospectroscopic characterization technique for soft tissue microstructure using site-matched confocal Raman microspectroscopy and polarized light microscopy. Using the technique, the microstructure of soft tissue samples is directly observed by polarized light microscopy during loading while spatially correlated spectroscopic information is extracted from the same plane,...

Correction of diffraction effects in confocal Raman microspectroscopy.

A mathematical approach developed to correct depth profiles of wet-chemically modified polymer films obtained by confocal Raman microscopy is presented which takes into account scattered contributions originated from a diffraction-limited laser focal volume. It is demonstrated that the problem can be described using a linear Fredholm integral equation of the first kind which correlates apparent...

Rapid identification of Candida species by confocal Raman microspectroscopy.

Candida species are important nosocomial pathogens associated with high mortality rates. Rapid detection and identification of Candida species can guide a clinician at an early stage to prescribe antifungal drugs or to adjust empirical therapy when resistant species are isolated. Confocal Raman microspectroscopy is highly suitable for the rapid identification of Candida species, since Raman spe...

Confocal Raman Microspectroscopy; Applications in Cartilage Tissue Engineering