منابع مشابه
A New S-test for Haplotype Analysis: Concordance and Discordance
A new test of inheritance, S, is proposed, which uses information from affected as well as unaffected siblings in the fam­ ily. The siblings are analyzed in terms of similarities of haplotypes. The distribution of the proposed S­test is derived under the null hypothesis of random inheritance. Mean and variance are obtained for the distribution. The test is then applied to data sets publ...
متن کاملTest S of Haplotype Concordance and Discordance
The test presented here is based upon the proband and his/her affected as well as unaffected siblings. Here, the siblings are analyzed in terms of similarities of haplotypes. The proposed ‘S’ test is used in testing hypothesis that a particular disease has random pattern of inheritance against the alternative hypothesis that it has non-random pattern of inheritance. Probability distribution, me...
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Outranking methods propose an original way to build a preference relation between alternatives evaluated on several attributes that has a definite ordinal flavor. Indeed, most of them appeal the concordance / non-discordance principle that leads to declaring that an alternative is “superior” to another, if the coalition of attributes supporting this proposition is “sufficiently important” (conc...
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According to the separate universe conjecture, spherically symmetric sub-regions in an isotropic universe behave like mini-universes with their own cosmological parameters. This is an excellent approximation in both Newtonian and general relativistic theories. We estimate local expansion rates for a large number of such regions, and use a scale parameter calculated from the volumeaveraged incre...
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It is generally accepted that the frequency of congenital heart disease is higher in relatives of patients than in the general population. Estimates both of population frequencies, and of the extent to which these frequencies are exceeded in relatives of those affected, vary considerably. This is not surprising as some authors have reported series diagnosed at birth, while others have reported ...
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ژورنال
عنوان ژورنال: Physical Review D
سال: 2019
ISSN: 2470-0010,2470-0029
DOI: 10.1103/physrevd.99.043506