Computational Models of Individual and Collective Keratocyte Migration

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Development of a Novel High Throughput Computational Tool for Studying Individual and Collective Cellular Migration

Understanding how cells migrate individually and collectively during development and cancer metastasis can be significantly aided by a computation tool to accurately measure not only cellular migration speed, but also migration direction and changes in migration direction in a temporal and spatial manner. We have developed such a tool for cell migration researchers, named Pathfinder, which is c...

متن کامل

Computational models of collective behavior.

Computational models of human collective behavior offer promise in providing quantitative and empirically verifiable accounts of how individual decisions lead to the emergence of group-level organizations. Agent-based models (ABMs) describe interactions among individual agents and their environment, and provide a process-oriented alternative to descriptive mathematical models. Recent ABMs provi...

متن کامل

Computational models of collective foraging.

In this paper the behaviour of a bee colony is modelled as society of communicating agents acting in parallel and synchronising their behaviour. Two computational approaches for defining the agents behaviour are introduced and compared. Their common features as well as the complementary aspects making them suitable for merging together into a more complex model.

متن کامل

Zebrafish keratocyte explants to study collective cell migration and reepithelialization in cutaneous wound healing.

Due to their unique motile properties, fish keratocytes dissociated from explant cultures have long been used to study the mechanisms of single cell migration. However, when explants are established, these cells also move collectively, maintaining many of the features which make individual keratocytes an attractive model to study migration: rapid rates of motility, extensive actin-rich lamellae...

متن کامل

Collective and Individual Migration following the Epithelial-Mesenchymal Transition

During cancer progression, malignant cells in the tumour invade surrounding tissues. This transformation of adherent cells to a motile phenotype has been associated with the epithelial-mesenchymal transition (EMT). Here, we show that EMT-activated cells migrate through micropillar arrays as a collectively advancing front that scatters individual cells. Individual cells with few neighbours dispe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Biophysical Journal

سال: 2018

ISSN: 0006-3495

DOI: 10.1016/j.bpj.2017.11.2144