Compressive force promotes chondrogenic differentiation and hypertrophy in midpalatal suture cartilage in growing rats
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چکیده
منابع مشابه
Icariin promotes directed chondrogenic differentiation of bone marrow mesenchymal stem cells but not hypertrophy in vitro
Icariin (ICA), a Traditional Chinese Medicine, has been demonstrated to be a promoting compound for extracellular matrix synthesis and gene expression of chondrocytes. However, whether ICA can act as a substitute for or cooperate with growth factors to directly promote stable chondrogenesis of bone marrow mesenchymal stem cells (BMSCs) remains unknown. In the present study, rat BMSCs were culti...
متن کاملCellular Midpalatal Suture Changes after Rapid Maxillary Expansion in Growing Subjects: A Case Report
The present case report aimed to investigate immediate histologic changes in midpalatal suture in humans following rapid maxillary expansion compared to control. Three patients (mean age 8.3 +/- 0.9 years) were enrolled in the case report and underwent midpalatal suture biopsy. Two patients underwent treatment before biopsy. The third patient did not show transversal maxillary deficiency and wa...
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OBJECTIVE This study investigated a novel approach to induce chondrogenic differentiation of human mesenchymal stem cells (hMSC). We hypothesized that a structured three-dimensional co-culture using hMSC and chondrocytes would provide chondroinductive cues to hMSC without inducing hypertrophy. METHOD In an effort to promote optimal chondrogenic differentiation of hMSC, we created bilaminar ce...
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Since articular cartilage has a limited regeneration potential, for developing biological therapies for cartilage regeneration it is important to study the mechanisms underlying chondrogenesis of stem cells. Bioluminescence assays can visualize a wide range of biological phenomena such as gene expression, signaling, metabolism, development, cellular movements, and molecular interactions by usin...
متن کاملEffect of Dietary Ascorbic Acid on Osteogenesis of Expanding Midpalatal Suture in Rats
OBJECTIVES After maxillary expansion, a long period of retention is necessary to prevent early relapse. Therefore, it is beneficial to accelerate bone formation in the expanding midpalatal suture to reduce relapse. This study was designed to evaluate the effect of dietary vitamin C on osteogenesis of rat midpalatal suture during expansion. MATERIALS AND METHODS Fifty-four male Wistar rats wer...
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ژورنال
عنوان ژورنال: The Anatomical Record
سال: 2000
ISSN: 0003-276X,1097-0185
DOI: 10.1002/1097-0185(20001201)260:4<392::aid-ar90>3.0.co;2-o