Comprehensive approach to hemophilia

Hemophilia A, B are X-linked recessive bleeding disorder that typically results from a deficiency of clotting factor VIII (FVIII) and IX (FIX). The severity the disease is determined according to FVIII FIX levels. A have similar symptoms both characterized by bleeding, particularly in large joints such as ankles, knees, elbows. Recurrent eventually causes progressive hemophilic arthropathy. Life-threatening hemorrhages may occur rarely. Treatment hemophilia has improved significantly recent years with concentrates. average life expectancy was