Composite PHB/Chitosan Microparticles Obtained by Spray Drying: Effect of Chitosan Concentration and Crosslinking Agents on Drug Relesase
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چکیده
منابع مشابه
effect of postharvest application of chitosan and calcium chloride on decay and quality attributes of sweet cherry
چکیده ندارد.
15 صفحه اولSynthesis and Sustained-Release Property of Drug-Loaded Chitosan Microspheres by Spray Drying Technique
In this paper, drug–loaded chitosan microspheres were prepared by spray drying technique, using glutaraldehyde as cross–linking agent and salicylic acid as model drug. Effects of formulation and process parameters on the morphology of chitosan microspheres were investigated. The drug loading and encapsulation efficiency were determined. In vitro release of the drug into phosphate buffer at 37 °...
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Piroxicam, an anti-inflammatory drug, exhibits poor water solubility and flow properties, poor dissolution and poor wetting. Consequently, the aim of this study was to improve the dissolution of piroxicam. Microparticles containing piroxicam were produced by spray drying, using isopropyl alcohol and water in the ratio of 40:60 v/v as solvent system, and spray chilling technology by melting the ...
متن کاملAlginate microparticles produced by spray-drying for oral insulin delivery
In spite of the prevalence of subcutaneous injections for insulin administration, there are several concerns associated with this mode of administration including injection anxiety, pain, cost, infection, and as a result an overall decrease in patient compliance (Khafagy 2007). This has prompted researchers to search for alternative delivery methods including transdermal, nasal, pulmonary, rect...
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ژورنال
عنوان ژورنال: Journal of the Brazilian Chemical Society
سال: 2014
ISSN: 0103-5053
DOI: 10.5935/0103-5053.20140129