Complex Physical Properties of an Adaptive, Self-Organizing Biological System

The physical interpretation of the functioning adaptive immune system, which has been thoroughly characterized on genetic and molecular levels, provides a unique opportunity to define an self-organizing biological system in its entirety. This paper describes configuration space model function, where directed chemical potentials constitute interactions. In sense, humoral adjusts potential all available antigenic molecules by tuning organizing network hierarchy sensor-effector molecules, antibodies. coupling sensors effectors allows adjust thermodynamic activity antigens antibodies, while organization helps minimize maximize diversity. Mathematically couples variance Gaussian distributed interaction energies exponentially effector maintain stationary state. process creates scale-free space, absolute corresponds node degree. interpretation, is ensemble carrying out {mu}N work, adjusting according changes surroundings. validity supported identifying flexibility index, corresponding variables thermodynamics science, confirming applicability system. Overall, this statistical immunity how self-organization arises from maintenance scale-free, with fractal topology.