Complex biosynthesis of RGMc/Hemojuvelin, a Muscle‐Enriched Regulator of Systemic Iron Metabolism
نویسندگان
چکیده
منابع مشابه
Complex biosynthesis of the muscle-enriched iron regulator RGMc.
The recently discovered repulsive guidance molecule c (RGMc or hemojuvelin) gene encodes a putative glycosylphosphatidylinositol (GPI)-anchored protein that is expressed in striated muscle and in liver. Mutations in this gene have been linked to the severe iron storage disease, juvenile hemochromatosis, although the mechanisms of action of RGMc in iron metabolism are unknown. As a first step to...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2006
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.20.4.a106-b