Complete genome sequence of Treponema pedis GNW45 isolated from dairy cattle with active bovine digital dermatitis in Korea
نویسندگان
چکیده
<italic>Treponema pedis</italic>, a fastidious anaerobic spirochete, is one of the main pathogens involved in development and progression bovine digital dermatitis (BDD), lameness-causing hoof infection cattle. Here, complete genome sequencing <italic>T. pedis</italic> GNW45 isolated from dairy cow infected with BDD, was presented. Libraries for long short reads were sequenced using PacBioRSII Illimuna HiSeqXTen platforms, respectively. De-novo assembly done reads, producing circular contig, by which aligned to generate more accurate sequence. The has total size 3,077,465 base pairs, 36.84% guanine-cytosine content. A 2,749 protein-coding sequences, seven ribosomal RNA’s, 45 transfer RNA’s annotated. Functional analysis revealed genes associated pathogenicity survivability complex pathobiome BDD. This study provided novel insights into survival pathogenic mechanisms GNW45.
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ژورنال
عنوان ژورنال: Journal of Animal Science and Technology
سال: 2023
ISSN: ['2055-0391', '2672-0191', '1598-9429', '2093-6281']
DOI: https://doi.org/10.5187/jast.2023.e61