Complement fixation in Q fever

Complement fixation in Q fever. I. Comparative evaluation of several technics.

Q fever, an acute febrile disease which had been prevalent among workers at slaughter-houses and live-stock dealers in Australia, was first described by Derric1) in 1937, and it was found by Burnet2) that the disease was caused by a sort of rickettsia, which was named Rickettsia burnetii by Derrick3) (afterwards Coxiella burnetii by Bengtson). In United States of America, Davis4) isolated from ...

Enzyme immunoassay for Q fever: comparison with complement fixation and immunofluorescence tests and dot immunoblotting.

Enzyme-linked immunosorbent assays (ELISA) for the detection of specific immunoglobulin G (IgG) and IgM antibodies were developed by using purified Coxiella burnetii cells. Variables, including type of microtiter plate, blocking agent, incubation conditions, antigen stability, and substrate type, were examined to achieve optimal ELISA performance. The reliabilities of the assay systems were com...

Indirect Complement Fixation in Foot-and-Mouth Disease

Q fever a Forgotten Disease in Iran

There have already been a few studies on Q fever in Iran and most of them go back to more than 50 years ago. Preliminary serologic studies on ruminants and febrile patients in Southeast Iran show a high seropositivity in this region. Misdiagnosis as well as poor attention of public health authorities to this infection can facilitate the epidemic spread of Q fever. Further studies on the diagnos...

Epidemiologic Investigation of Acute Q Fever in North of Iran

 Background and purpose: Q fever is a worldwide zoonosis which is an endemic in many regions. Its diagnosis is usually missed especially in human. This research aimed at investigating acute Q fever among suspected patients in northern Iran. Materials and methods: This cross-sectional study was conducted in 56 suspected cases of Q fever selected from 476 febrile patients admitted in Qaemshahr R...