Complement activation in uveitis.

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Complement activation in uveitis.

To determine whether complement is activated in uveitis we have measured plasma levels of C3d, a sensitive indicator of complement activation. Increased levels of C3d were found in 11 of 15 patients with idiopathic uveitis, 13 of whom had circulating immune complexes containing complement components. Since during complement activation potent mediators of inflammation are generated, it is sugges...

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refractive errors changes during uveitis activation phase

purpose: to evaluate the role of active uveitis on refractive errors changes. methods: a cohort single group study was conducted on patients with acute or recurrent uveitis. cyclorefraction was performed in both phases of active and quiescent. sphere, cylinder and sphere equivalent power were compared in active and quiescent phases and analyzed statistically. results: sixty-six patients (eighty...

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Complement Activation

The complement system is the most important biochemical cascade in the blood for the recognition, opsonization, and elimination of foreign materials. To date, the leading causes of death in the United States include cancer, cardiovascular and neurodegenerative diseases, and diabetes. New treatments are urgently needed to treat these devastating diseases and nanotechnology potentially provides n...

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VITRECTOMY IN CHRONIC UVEITIS

Vitrectomy was performed on 25 eyes in 21 patients with chronic uveitis from various etiologies. Postoperative follow up averaged 22.8 months with visual improvement in 24 of 25 eyes. In this retrospective study, the techniques employed and the beneficial effect of vitrectomy alone or vitrectomy combined with cataract surgery (Iensectomy in most cases) on improving vision and decreasing th...

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Complement activation in sudden deafness.

OBJECTIVE To test whether complement activation is associated with sudden deafness. DESIGN Plasma samples obtained from patients in the acute phase of sudden deafness were analyzed for complement activation measured by C3bc levels and terminal complement complex. Comparisons were made with plasma samples from healthy controls. PATIENTS Twenty-five adult patients with unilateral sudden deafn...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1986

ISSN: 0007-1161

DOI: 10.1136/bjo.70.1.60