Competitive Adsorption: A Physical Model for Lung Surfactant Inactivation
نویسندگان
چکیده
منابع مشابه
Competitive adsorption: a physical model for lung surfactant inactivation.
Charged, surface-active serum proteins can severely reduce or eliminate the adsorption of lung surfactant from the subphase to the alveolar air-liquid interface via a kinetically controlled competitive adsorption process. The decreased surfactant concentration at the interface leads to higher surface tensions during the compression of the interface during breathing. The correspondence between t...
متن کاملA Mathematical Model for Adsorption of Surfactant onto Powdered Activated Carbon
The main objectives of this study were to remove surface-active agents and to predict the adsorption rejection models. The effects of surfactant concentration and PAC amount on the adsorption were determined. For both surfactants, It was found that the adsorption values also increased when PAC amount increased. It was observed that the rejection values are different for the adsorption of C...
متن کاملCompetitive Adsorption of Lung Surfactant and Serum Proteins at the Air-Liquid Interface: A Grazing Incidence X-Ray Diffraction Study
The competitive adsorption of lung surfactant (LS) and albumin at the air-liquid interface and the ability of polyethylene glycol (PEG) to mediate LS adsorption are analyzed using pressure-area isotherms and grazing incidence x-ray diffraction (GIXD). The addition of albumin drastically reduces the amount of LS on the interface and slightly increases the LS lattice spacing. The addition of PEG ...
متن کاملX-ray diffraction and reflectivity validation of the depletion attraction in the competitive adsorption of lung surfactant and albumin.
Lung surfactant (LS) and albumin compete for the air-water interface when both are present in solution. Equilibrium favors LS because it has a lower equilibrium surface pressure, but the smaller albumin is kinetically favored by faster diffusion. Albumin at the interface creates an energy barrier to subsequent LS adsorption that can be overcome by the depletion attraction induced by polyethylen...
متن کاملModel for Competitive Adsorption of Organic Cations on Clays
-The adsorption on montmorillonite of two monovalent organic cations, methylene blue (MB) and thioflavin T (TFT), was studied in four different situations: (1) separate adsorption of MB or TFT; (2) competitive adsorption of TFT and Cs; (3) competitive adsorption of the two organic cations from their equimolar solutions; and (4) adsorption of TFT on a clay whose cation-exchange capacity (CEC) ha...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Langmuir
سال: 2009
ISSN: 0743-7463,1520-5827
DOI: 10.1021/la8039434