Comparison of Post-Procedural and 30-day Post-Implantation Transcatheter Aortic Valve Replacement Gradients with and without pre-implantation Balloon Valvuloplasty: A Real-World Analysis of Early Results using a Novel Balloon Expandable Transcatheter Aortic Valve

Objectives: This study describes a real-world experience of implanting novel balloon expandable transcatheter aortic valve replacement (TAVR) compared to devices commonly used in clinical practice. As secondary objective, the effect angioplasty (BAV) before TAVR on transvalvular gradient 1 and 30 days after implantation was evaluated. Background: For most commercial valves, 30-day average mean gradients have been reported. Our with Lotus Valve System had indicated higher immediate post-implant than those literature. We sought evaluate both these comparing them other valves. Methods: analyzed discharge echocardiograms valves from 7/5/2019 8/27/2020. In response higher-than-expected gradients, patients 11/4/19 8/27/20 underwent BAV implantation, whereas 7/5/19 10/18/19 did not (no-BAV). samples each random sampling implanted by same interventionalist. Results: At discharge, 27 received The 16.7 mmHg (SD = 5.5 mmHg) for no-BAV 14.7 3.7 (P 0.177) cohorts. No-BAV were significantly < 0.001) Sapien (M 12 mmHg, SD 4.3) CoreValve 9.18 3.96). assessment, groups similar literature 11 3.5; M 4.1 0.287)) Conclusions: demonstrated post-implantation attenuated BAV. These elevated significant at follow-up.