Comparison of modification sites formed on human serum albumin at various stages of glycation
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چکیده
منابع مشابه
Comparison of modification sites formed on human serum albumin at various stages of glycation.
BACKGROUND Many of the complications encountered during diabetes can be linked to the non-enzymatic glycation of proteins, including human serum albumin (HSA). However, there is little information regarding how the glycation pattern of HSA changes as the total extent of glycation is varied. The goal of this study was to identify and conduct a semi-quantitative comparison of the glycation produc...
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Glycation involves the non-enzymatic addition of reducing sugars and/or their reactive degradation products to amine groups on proteins. This process is promoted by the presence of elevated blood glucose concentrations in diabetes and occurs with various proteins that include human serum albumin (HSA). This review examines work that has been conducted in the study and analysis of glycated HSA. ...
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ژورنال
عنوان ژورنال: Clinica Chimica Acta
سال: 2011
ISSN: 0009-8981
DOI: 10.1016/j.cca.2010.10.018